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Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 μg/mL[1].

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (1) Acetyl-CoA Carboxylase (1) Adrenergic Receptor (1) Antibiotic (10) Apoptosis (2) Autophagy (2) Bacterial (32) Calcium Channel (2) COX (1) DNA/RNA Synthesis (1) Dynamin (1) EAAT (1) Endogenous Metabolite (17) Fluorescent Dye (3) Fungal (23) HCV (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (1) Histone Acetyltransferase (1) HSV (1) Influenza Virus (1) Isotope-Labeled Compounds (14) Leukotriene Receptor (1) MDM-2/p53 (1) mTOR (2) NO Synthase (1) Nucleoside Antimetabolite/Analog (2) Opioid Receptor (1) Orthopoxvirus (1) P-glycoprotein (1) Parasite (3) PARP (1) Potassium Channel (2) PROTAC Linkers (1) Reactive Oxygen Species (2) SARS-CoV (1) Sodium Channel (2) Thrombopoietin Receptor (1) Thymidylate Synthase (1) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Endocrinology (1) Infection (50) Inflammation/Immunology (8) Metabolic Disease (3) Neurological Disease (7)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (1) Tetrazine (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: ADAMTS Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106472

Tioxaprofen EMD 26644	Bacterial	Infection
Tioxaprofen is a new anti-mycotic drug against Trichophyton mentagrophytes and T. rubrum, and is a potent uncoupling agent of mitochondrial respiration .

HY-N11434

Anisocoumarin H	Fungal	Infection
Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL .

HY-N11079

Toonaciliatin M	Fungal	Infection
Toonaciliatin M (compound 6) is a pmaradiene-type diterpenoid that can be isolated from Toona ciliate. Toonaciliatin M show antifungal activity against Trichophyton rubrum with an *MIC* value of 12.5 µg/mL .

HY-N8726

Neophellamuretin

Fungal Infection

Neophellamuretin is a flavonoid. Neophellamuretin inhibits Trichophyton sp. with an MIC value of 62.5 µg/mL .
HY-124555

Hexamide

Benzimine
Fungal Infection

Hexamide (Benzamine) is a fungal inhibitor. Hexamide is effective against Trichophyton .
HY-149778

Antifungal agent 87

Fungal Infection

Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC₅₀ = 1 nM for T. rubrum) .

Neophellamuretin	Fungal	Infection
Neophellamuretin is a flavonoid. Neophellamuretin inhibits Trichophyton sp. with an *MIC* value of 62.5 µg/mL .

Hexamide Benzimine	Fungal	Infection
Hexamide (Benzamine) is a fungal inhibitor. Hexamide is effective against Trichophyton .

Antifungal agent 87	Fungal	Infection
Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC₅₀ = 1 nM for T. rubrum) .

HY-108012

ME1111	Fungal	Infection
ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research .

HY-N8329

AS-2077715	Fungal Antibiotic	Infection
AS-2077715 is an antifungal agent that shows inhibitory activity against the Trichophyton species. AS-2077715 can be obtained from the fermentation broth of Capnodium sp. 339855. AS-2077715 can be used to study fungal infections .

HY-P1508

Bactenecin Bactenecin, bovine	Bacterial Fungal Antibiotic	Infection
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* .

HY-148160

Diamthazole

Dimazole
Fungal Infection

Diamthazole (Dimazole) is an antifungal agent. Diamthazole can be used for the research of infection .

Diamthazole Dimazole	Fungal	Infection
Diamthazole (Dimazole) is an antifungal agent. Diamthazole can be used for the research of infection .

HY-148160A

Diamthazole hydrochloride Dimazole hydrochloride	Fungal	Infection
Diamthazole (Dimazole) hydrochloride is an antifungal agent. Diamthazole hydrochloride can be used for the research of infection .

HY-P1508A

Bactenecin TFA Bactenecin, bovine TFA	Bacterial Fungal	Infection
Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* .

HY-N7307

Pachybasin	Bacterial	Infection
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

HY-15660

Efinaconazole 1 Publications Verification KP-103	Fungal	Infection
Efinaconazole (KP-103) is a triazole antifungal agent and againsts *T. mentagrophytes* SM-110** and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .

HY-147814

KFU-127	Bacterial Fungal	Infection
KFU-127 (Compound 6b) is a broad spectrum topical antimicrobial capable of one-shot targeting of bacterial and fungal-bacterial biofilms. KFU-127 is considerably toxic for eukaryotic cells . KFU-127 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-15306S

Eltrombopag-13C4 1 Publications Verification SB-497115-<sup>13sup>C₄	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-W004282S

Undecanoic acid-d21 Undecanoate-d₂₁; Hendecanoic acid-d₂₁	Fungal Endogenous Metabolite	Cancer
Undecanoic acid-d₂₁ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-W004282S1

Undecanoic acid-d3 Undecanoate-d₃; Hendecanoic acid-d₃	Fungal Endogenous Metabolite
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-W004282S2

Undecanoic acid-d2 Undecanoate-d₂; Hendecanoic acid-d₂	Fungal Endogenous Metabolite
Undecanoic acid-d₂ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-151551

Mtb-cyt-bd oxidase-IN-4	Bacterial	Infection
Mtb-cyt-bd oxidase-IN-4 (compound 1g) is a Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) inhibitor with an IC₅₀ value of 0.25 μM. Mtb-cyt-bd oxidase-IN-4 inhibits the growth of Mycobacterium tuberculosis (MIC=8 μM). Mtb-cyt-bd oxidase-IN-4 can be used in tuberculosis research .

HY-15660S

Efinaconazole-d4 KP-103-d₄	Isotope-Labeled Compounds Fungal	Infection
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].

HY-143292

Antibacterial agent 81	Bacterial	Infection
Antibacterial agent 81 is a DNA transcription inhibitor. Antibacterial agent 81 inhibits S. aureus USA300 and M. smegmatis ATCC14468 with *MIC* values of 12.5 and 7.8 μM, respectively. Antibacterial agent 81 can be used for the research of infection .

HY-108166

Hydroxystilbamidine	Fluorescent Dye	Inflammation/Immunology
Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain ^{[1]sup .}

HY-145128

GR103545	Opioid Receptor	Neurological Disease
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). ¹¹GR103545 is a radiotracer for imaging κ-OR in vivo ^{[1]sup .}

HY-126906

Milbemycin A4	Antibiotic P-glycoprotein	Cancer
Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity ^[1]sup>[2].

HY-W011509

CyPPA	Potassium Channel	Neurological Disease
CyPPA is a positive modulator of hSK3 and hSK2, with EC₅₀ values of 14 μM and 5.6 μM, repectively. CyPPA is inactive on both hSK1 and hIK channels ^{[1]sup .}

HY-161263

Antibacterial agent 182	Bacterial	Infection
Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL). Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses .

HY-129384

Rubratoxin B

Others Cancer

Rubratoxin B is a hepatotoxic mycotoxin that can be found in Penicillium rubrum Stoll. Rubratoxin B shows antitumor activity .

Rubratoxin B	Others	Cancer
Rubratoxin B is a hepatotoxic mycotoxin that can be found in Penicillium rubrum* Stoll*. Rubratoxin B shows antitumor activity .

HY-107064

Cefroxadine CGP 9000; Oraspor	Bacterial Antibiotic	Infection
Cefroxadine (CGP 9000) is an orally active cephalosporin antibiotic. Cefroxadine is more effective than cephalexin against Escherichia coli and Klebsiella pneumoniae with *MIC* values of 3.13 and 1.56 μg/mL respectively with a concentration of 10 ⁶ μg/mL. Cefroxadine can be used for the research of infection .

HY-10980

Tavaborole 1 Publications Verification AN-2690	Fungal Antibiotic	Infection
Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis.

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Others	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-W004282

Undecanoic acid Undecanoate; Hendecanoic acid	Fungal Endogenous Metabolite	Infection
Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum .

HY-151549

Mtb-cyt-bd oxidase-IN-2	Bacterial	Infection
Mtb-cyt-bd oxidase-IN-2 is an inhibitor of Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) with an IC₅₀ value of 0.67 μM. Mtb-cyt-bd oxidase-IN-2 inhibits the growth of Mycobacterium tuberculosis with a *MIC* value of 256 μM. Mtb-cyt-bd oxidase-IN-2 can be used for the research of infection .

HY-161119

Drpitor1a	Dynamin Reactive Oxygen Species	Cardiovascular Disease Cancer
Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer ^{[1]sup .}

HY-143290

Antibacterial agent 118	Bacterial	Infection
Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with *MIC* values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis .

HY-Y0921S3

(±)-1,2-Propanediol-13C3 1,2-(RS)-Propanediol-<sup>13sup>C₃; 1,2-Propylene glycol-<sup>13sup>C₃; Propylene glycol-<sup>13sup>C₃	Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-12741

LDN-212320 4 Publications Verification LDN-0212320; OSU-0212320	EAAT	Neurological Disease
LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC ^{[1]sup .}

HY-19584

Variotin
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .

HY-N8824

Maackiaflavanone

Others Others

Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

Maackiaflavanone	Others	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-135770

9-Dehydroxyeurotinone	Others	Cancer
9-Dehydroxyeurotinone is an anthraquinone derivative that can be found in Eurotium rubrum. 9-Dehydroxyeurotinone shows cytotoxicity with an IC₅₀ value of 25 µg/mL for SW1990 cells .

HY-138050

Nyasol (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol	NO Synthase Bacterial Fungal Parasite Leukotriene Receptor	Infection Inflammation/Immunology
Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .

HY-137048

PF-00835231 1 Publications Verification	SARS-CoV	Infection
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CL ^pro) inhibitor, with IC₅₀s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CL ^pro, respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19 ^[1]sup>[2].

HY-W004282R

Undecanoic acid (Standard) Undecanoate (Standard); Hendecanoic acid (Standard)	Fungal Endogenous Metabolite	Infection Cancer
Undecanoic acid (Standard) is the analytical standard of Undecanoic acid. This product is intended for research and analytical applications. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum .

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Antibiotic Bacterial	Infection
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-N5142

α-Terpineol	Bacterial	Infection Inflammation/Immunology
α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria . α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-N3837

Epitaraxerol Isotaraxerol; 3α-Taraxerol	Bacterial	Infection
Epitaraxerol (compound 6) is a natural product isolated from the leaves of E. neriifolia. Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes,* A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis .*

HY-N3344

Macrocarpal C	Fungal	Others
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .

HY-157143

Antibacterial agent 164	Bacterial	Infection
Antibacterial agent 164 (compound 2a) is an antibacterial and antibiofilm agent. Antibacterial agent 164 inhibits S. aureus and B. subtilis (MIC of 0.09 mM), and also exhibits strong anti-B. Subtilis biofilm formation .

HY-N3872

Ethyl β-D-glucopyranoside	Others	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-P4210

Sulanemadlin ALRN-6924; MP-4897	MDM-2/p53	Cancer
Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .

Cat. No.	Product Name	Target	Research Area

HY-P1508A

Bactenecin TFA Bactenecin, bovine TFA	Bacterial Fungal	Infection
Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* .

HY-P4210

Sulanemadlin ALRN-6924; MP-4897	MDM-2/p53	Cancer
Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .

HY-P1508

Bactenecin Bactenecin, bovine	Bacterial Fungal Antibiotic	Infection
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* .

HY-P4583

Suc-Val-Pro-Phe-SBzl

Peptides Others

Suc-Val-Pro-Phe-SBzl (succinyl-valine-proline-phenylalanine thiobenzyl ester) is an inhibitor of CatG enzymes with IC₅₀ values of 111-225 mM.

HY-P5984

Thioether-cyclized helix B peptide, CHBP	mTOR	Others
Thioether-cyclized helix B peptide, CHBP can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .

HY-P5984A

Thioether-cyclized helix B peptide, CHBP TFA	mTOR	Others
Thioether-cyclized helix B peptide, CHBP (TFA) is the TFA form of Thioether-cyclized helix B peptide, CHBP (HY-P5984). Thioether-cyclized helix B peptide, CHBP (TFA) can improve metabolic stability and renoprotective effect through inducing autophagy via inhibition of mTORC1 and activation of mTORC2 .

HY-P5145

μ-Conotoxin PIIIA

Sodium Channel Inflammation/Immunology

μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. μ-Conotoxin PIIIA can be isolated from Conus purpurascens .

HY-P5864

µ-Conotoxin BuIIIA	Sodium Channel	Neurological Disease
μ-Conotoxin BuIIIA (Mu-Conotoxin BuIIIA) is a voltage-gated sodium channel (VGSC) blocker. μ-Conotoxin BuIIIA is a toxic peptide that can be obtained from the venom of Cone snails. μ-Conotoxin BuIIIA can be used in the study of neurological diseases .

HY-P5804

ω-Conotoxin CVIF	Calcium Channel	Neurological Disease
ω-Conotoxin CVIF is a selective Ca_v2.2 channel inhibitor with an IC₅₀ of 34.3 nM in rat isolated DRG neurons. ω-Conotoxin CVIF block of Cav2.2 channels is weakly reversible .

HY-P5143

ω-Conotoxin SO3	Calcium Channel	Inflammation/Immunology
ω-Conotoxin SO3 is a blocker of N-type voltage-sensitive calcium channel. ω-Conotoxin SO3 is an analgesicω-conotoxin that can be isolated from the venom of C. striatus .

HY-P5563

PP113	Bacterial	Infection
PP113 is an antimicrobial peptide is active against Gram-negative and Gram-positive bacteria, E.coli (MIC: 73.3 uM), B. subtilis (MIC: 23.3 uM), S. aureus (MIC: 13 uM), S. lutea (MIC: 16.7 uM), and B. pumilu (MIC: 23.3 uM) .

HY-P5562

PP102	Bacterial	Infection
PP102 is an antimicrobial peptide is active against gram-positive B. subtilis (MIC: 25 uM), S. aureus (MIC: 13.3 uM), S. lutea (MIC: 63 uM), and B. pumilu (MIC: 23 uM) .

HY-P5944

Deamino-pterinotoxin-1

Peptides Others

Deamino-pterinotoxin-1 is a peptide toxin synthesized from the deamination of pterinotoxin-1 (HY-5943) .

HY-P5560

PP13	Bacterial	Infection
PP13 is an antimicrobial peptide, and is active against Gram-negative and Gram-positive bacteria E.coli (MIC: 16.7 uM), B. subtilis (MIC: 13.3 uM), S. aureus (MIC: 23.3 uM), S. lutea (MIC: 8.0 uM), and B. pumilu (MIC: 9.0 uM) .

HY-P1426

AmmTX3	Potassium Channel	Inflammation/Immunology
AmmTX3 is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 is specific blocker of K_v4 channel. AmmTX3 inhibits the A-type K ⁺ current (K_i: 131 nM) .

HY-P5740

Cacaoidin	Bacterial	Infection
Cacaoidin is a glycosylated lantibiotic isolated from a Streptomyces cacaoi strain. Cacaoidin has potent antibacterial activity against Gram-positive pathogens including Clostridium difficile .

HY-161423

Antimicrobial agent-28	Bacterial	Infection
Antimicrobial agent-28 (Compound Bicycle molecule) is an antibacterial agent with good affinity for the penicillin-binding protein (PBP3) of Escherichia coli, which can inhibit the activity of Escherichia coli .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N11434

Anisocoumarin H	Structural Classification Source classification Coumarins Phenylpropanoids Plants Baccharis darwinii Hook. & Arn. Compositae	Fungal
Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL .

HY-N11079

Toonaciliatin M	Structural Classification Terpenoids Source classification Toona ciliata var. pubescens Diterpenoids Plants Meliaceae	Fungal
Toonaciliatin M (compound 6) is a pmaradiene-type diterpenoid that can be isolated from Toona ciliate. Toonaciliatin M show antifungal activity against Trichophyton rubrum with an *MIC* value of 12.5 µg/mL .

HY-N8726

Neophellamuretin	Structural Classification Flavonols Flavonoids Ohwia caudata (Thunberg) H. Ohashi Leguminosae Source classification Plants	Fungal
Neophellamuretin is a flavonoid. Neophellamuretin inhibits Trichophyton sp. with an *MIC* value of 62.5 µg/mL .

HY-N8329

AS-2077715	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Antibiotic
AS-2077715 is an antifungal agent that shows inhibitory activity against the Trichophyton species. AS-2077715 can be obtained from the fermentation broth of Capnodium sp. 339855. AS-2077715 can be used to study fungal infections .

HY-P1508

Bactenecin Bactenecin, bovine	Infection Structural Classification Classification of Application Fields Animals Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Fungal Antibiotic
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* .

HY-P1508A

Bactenecin TFA Bactenecin, bovine TFA	Infection Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial Fungal
Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* .

HY-N7307

Pachybasin	Infection Quinones Monophenols Microorganisms Classification of Application Fields Anthraquinones Source classification Phenols Disease Research Fields	Bacterial
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-W004282

Undecanoic acid Undecanoate; Hendecanoic acid	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Fungal Endogenous Metabolite
Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum .

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-135770

9-Dehydroxyeurotinone	Structural Classification Natural Products Microorganisms Source classification	Others
9-Dehydroxyeurotinone is an anthraquinone derivative that can be found in Eurotium rubrum. 9-Dehydroxyeurotinone shows cytotoxicity with an IC₅₀ value of 25 µg/mL for SW1990 cells .

HY-138050

Nyasol (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol	Structural Classification Source classification Phenols Polyphenols Hypoxis angustifolia Lam. Plants Asparagaceae Juss.	NO Synthase Bacterial Fungal Parasite Leukotriene Receptor
Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .

HY-W004282R

Undecanoic acid (Standard) Undecanoate (Standard); Hendecanoic acid (Standard)	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Fungal Endogenous Metabolite
Undecanoic acid (Standard) is the analytical standard of Undecanoic acid. This product is intended for research and analytical applications. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum .

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-N5142

α-Terpineol	Structural Classification Classification of Application Fields Source classification Plants Infection Other Monoterpenes Saururaceae Microorganisms Terpenoids Myrtaceae Eucalyptus globulus Labill. Inflammation/Immunology Disease Research Fields	Bacterial
α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria . α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-N3837

Epitaraxerol Isotaraxerol; 3α-Taraxerol	Triterpenes Structural Classification Excoecaria agallocha L. Terpenoids Source classification Euphorbiaceae Plants	Bacterial
Epitaraxerol (compound 6) is a natural product isolated from the leaves of E. neriifolia. Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes,* A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis .*

HY-N3344

Macrocarpal C	Structural Classification Source classification Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill.	Fungal
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-N12096

Galbinic acid α-Acetylsalazinic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Polyphenols	Bacterial
Galbinic acid (α-Acetylsalazinic acid), a lichen acid, shows antibacterial activities against the Gram-positive bacteria B. cereus, B. subtilis, and S. aureus (MICs=62.5, 62.5, 250 μg/ml, respectively). Galbinic acid inhibits the Gram-negative bacterium E. coli (MIC=125 μg/ml) .

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Galinsoga parviflora Cav. Flavonoids Flavones Labiatae Source classification Plants	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

Species:	Human (61) Rhesus Macaque (2) Mouse (19) Rat (3) Cynomolgus (3)
Tag:	His (52) SUMO (1) Tag Free (11) Strep (2) Avi (3) Myc (3) GST (3) Fc (22) Flag (2)
Source:	HEK293 (55) E. coli Cell-free (3) Sf9 insect cells (8) E. coli (22)

Cat. No.	Compare	Product Name	Species	Source

HY-P77235

	TIGIT Protein, Mouse (HEK293, mFc) T cell immunoreceptor with Ig and ITIM domains; TIGIT; VSIG9; VSTM3	Mouse	HEK293
	TIGIT protein, with signaling receptor binding activity, functions upstream of T cell activation suppression. Active on the cell surface, it shares orthology with human TIGIT. Associated with modulating T cell responses, TIGIT exhibits biased expression, notably in the large intestine, small intestine, and other tissues. This highlights its potential in immune regulation within these contexts. TIGIT Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived TIGIT protein, expressed by HEK293 , with C-mFc labeled tag. The total length of TIGIT Protein, Mouse (HEK293, mFc) is 125 a.a., with molecular weight of ~39-52 KDa.

HY-P71009

	TIGIT Protein, Mouse (118a.a, HEK293, Fc) T-cell immunoreceptor with Ig and ITIM domains; Tigit	Mouse	HEK293
	TIGIT protein, with signaling receptor binding activity, functions upstream of T cell activation suppression. Active on the cell surface, it shares orthology with human TIGIT. Associated with modulating T cell responses, TIGIT exhibits biased expression, notably in the large intestine, small intestine, and other tissues. This highlights its potential in immune regulation within these contexts. TIGIT Protein, Mouse (118a.a, HEK293, Fc) is the recombinant mouse-derived TIGIT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TIGIT Protein, Mouse (118a.a, HEK293, Fc) is 118 a.a., with molecular weight of 50-60 kDa.

HY-P70050

	CRADD Protein, Human rHuDeath domain-containing protein CRADD/CRADD; Death Domain-Containing Protein CRADD; Caspase and RIP Adapter with Death Domain; RIP-Associated Protein with A Death Domain; CRADD; RAIDD	Human	E. coli
	As an adapter protein, CRADD forms a PIDDosome complex with PIDD1 and CASP2, activates CASP2 and initiates apoptosis. It also recruits CASP2 to the TNFR-1 signaling complex in the tumor necrosis factor-mediated pathway, interacting with RIPK1 and TRADD. CRADD Protein, Human is the recombinant human-derived CRADD protein, expressed by E. coli , with tag free. The total length of CRADD Protein, Human is 199 a.a., with molecular weight of ~21.0 kDa.

HY-P72418

	TIGIT Protein, Human (HEK293, His-Avi) T-cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3	Human	HEK293
	TIGIT Protein plays a pivotal role in immune regulation, binding with high affinity to the poliovirus receptor (PVR). This interaction induces an immunosuppressive environment by increasing IL10 secretion and decreasing IL12B secretion. TIGIT suppresses T-cell activation, promotes mature immunoregulatory dendritic cell generation, and forms a homodimer in cis with high-affinity PVR binding. It also exhibits lower-affinity binding to NECTIN2 and NECTIN3, showcasing diverse molecular interactions. TIGIT's multifaceted functions underscore its crucial role in immune regulation and its potential as a therapeutic target for modulating immune responses. TIGIT Protein, Human (HEK293, His-Avi) is the recombinant human-derived TIGIT protein, expressed by HEK293, with C-Avi, C-6*His labeled tag. The total length of TIGIT Protein, Human (HEK293, His-Avi) is 120 a.a., with molecular weight of 17-23 kDa.

HY-P76674

	TIGIT Protein, Cynomolgus (HEK293, Fc) T cell immunoreceptor with Ig and ITIM domains; TIGIT; VSIG9; VSTM3	Cynomolgus	HEK293
	TIGIT is a receptor of the Ig superfamily that plays a key role in restricting adaptive and innate immunity. TIGIT can be used as an immune modulator to inhibit the activity of T cells and NK cells, and also regulates the recognition of cancer cells. TIGIT consists of an extracellular immunoglobulin (Ig) variable domain, a type 1 transmembrane domain, and a cytoplasmic tail with two inhibitory motifs. TIGIT Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived TIGIT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TIGIT Protein, Cynomolgus (HEK293, Fc) is 183 a.a., with molecular weight of ~47.2 kDa.

HY-P72449

	TIGIT Protein, Mouse (110a.a, HEK293, His) T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and transmembrane domain-containing protein 3; VSTM3	Mouse	HEK293
	TIGIT protein, with signaling receptor binding activity, functions upstream of T cell activation suppression. Active on the cell surface, it shares orthology with human TIGIT. Associated with modulating T cell responses, TIGIT exhibits biased expression, notably in the large intestine, small intestine, and other tissues. This highlights its potential in immune regulation within these contexts. TIGIT Protein, Mouse (110a.a, HEK293, His) is the recombinant mouse-derived TIGIT protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIGIT Protein, Mouse (110a.a, HEK293, His) is 110 a.a., with molecular weight of 15-22 kDa.

HY-P7414

	TIGIT Protein, Human (HEK293, Fc) rHuTIGIT, Fc Chimera; VSIG9; VSTM3; T Cell Immunoreceptor with Ig and ITIM Domains	Human	HEK293
	TIGIT Protein, Human (HEK293, Fc) produced in HEK293 cells is a polypeptide chain containing 352 amino acids with the C-termimal human IgG1 Fc fragment. T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3). It belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM).

HY-P70677

	TIGIT Protein, Cynomolgus (HEK293, His) T-cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3; TIGIT; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9	Cynomolgus	HEK293
	Ig-like domain-containing protein is a class of proteins that may be involved in protein–protein and protein–ligand interactions, therefore being involved in biological processes such as down-regulation of T cell activation or cardiac and neuronal development. TIGIT Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TIGIT protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIGIT Protein, Cynomolgus (HEK293, His) is 121 a.a., with molecular weight of 16-30 kDa.

HY-P71363

	TIGIT Protein, Human (HEK293, mFc) T-cell immunoreceptor with Ig and ITIM domains; ; VSIG9; VSTM3; TIGIT; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9	Human	HEK293
	The TIGIT protein plays a key role in immune regulation and binds with high affinity to the poliovirus receptor (PVR). This interaction induces an immunosuppressive environment by increasing IL10 secretion and decreasing IL12B secretion. TIGIT Protein, Human (HEK293, mFc) is the recombinant human-derived TIGIT protein, expressed by HEK293 , with C-mFc labeled tag. The total length of TIGIT Protein, Human (HEK293, mFc) is 120 a.a., with molecular weight of 40-50 kDa.

HY-P71007

	TIGIT Protein, Cynomolgus (HEK293, C-hFc) T-cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3; TIGIT; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9	Cynomolgus	HEK293
	Ig-like domain-containing protein is a class of proteins that may be involved in protein–protein and protein–ligand interactions, therefore being involved in biological processes such as down-regulation of T cell activation or cardiac and neuronal development. TIGIT Protein, Cynomolgus (HEK293, C-hFc) is the recombinant cynomolgus-derived TIGIT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TIGIT Protein, Cynomolgus (HEK293, C-hFc) is 121 a.a., with molecular weight of 45-55 kDa.

HY-P74513

	TIGIT Protein, Rat (137a.a, HEK293, Fc) T cell immunoreceptor with Ig and ITIM domains; TIGIT; VSIG9; VSTM3	Rat	HEK293
	T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins, binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation or T cell dependent B cell responses by promoting the generation of mature immunoregulatory dendritic cells. TIGIT Protein, Rat (137a.a, HEK293, Fc) is the recombinant rat-derived TIGIT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TIGIT Protein, Rat (137a.a, HEK293, Fc) is 121 a.a., with molecular weight of ~48-58 kDa.

HY-P70624

	TIGIT Protein, Human (120a.a, HEK293, His) T-cell immunoreceptor with Ig and ITIM domains; ; VSIG9; VSTM3; TIGIT; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9	Human	HEK293
	The TIGIT protein plays a key role in immune regulation and binds with high affinity to the poliovirus receptor (PVR). This interaction induces an immunosuppressive environment by increasing IL10 secretion and decreasing IL12B secretion. TIGIT Protein, Human (120a.a, HEK293, His) is the recombinant human-derived TIGIT protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIGIT Protein, Human (120a.a, HEK293, His) is 120 a.a., with molecular weight of 16-18 kDa.

HY-P76684

	TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc) TR-1; H7365; Transmembrane protein with EGF-like and one follistatin-like domain; C9orf2	Human	HEK293
	TMEFF1/Tomoregulin-1 protein may inhibit NODAL and BMP signaling in neural patterning, suggesting a regulatory role in neural development. It has been proposed as a tumor suppressor in brain cancer, emphasizing its importance in mitigating abnormal cell growth. TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc) is the recombinant human-derived TMEFF1/Tomoregulin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc) is 291 a.a., with molecular weight of ~65 kDa.

HY-P77252

	TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc) TR-1; H7365; Transmembrane protein with EGF-like and one follistatin-like domain; C9orf2	Mouse	HEK293
	TMEFF1/Tomoregulin-1 Protein is a transmembrane protein involved in the physiological functions of the central nervous system, embryonic development, and other biological processes. TMEFF1 may inhibit NODAL and BMP signaling during neural patterning. And it may be a tumor suppressor in brain cancers. Additionally, the protein may interact with ST14, implying a molecular association that may contribute to its regulatory and signaling functions. TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TMEFF1/Tomoregulin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc) is 298 a.a., with molecular weight of ~69 kDa.

HY-P700470

	TMEFF2/Tomoregulin-2 Protein, Human (HEK293, His) TMEFF2; transmembrane protein with EGF like and two follistatin like domains 2; TR; HPP1; TPEF; TR-2; TENB2; CT120.2; tomoregulin-2; cancer/testis antigen family 120, member 2; hyperplastic polyposis protein 1; transmembrane protein TENB2; transmembrane protein with EGF-like and two follistatin-like domains	Human	HEK293
	TMEFF2/Tomoregulin-2 protein serves as a potential survival factor for hippocampal and midbrain neurons, supporting neuronal cell viability. In addition, its shed form may upregulate cancer cell proliferation by promoting ERK1/2 phosphorylation. TMEFF2/Tomoregulin-2 Protein, Human (HEK293, His) is the recombinant human-derived TMEFF2/Tomoregulin-2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of TMEFF2/Tomoregulin-2 Protein, Human (HEK293, His) is 280 a.a., with molecular weight of 32.3 kDa.

HY-P701540

	CHFR Protein, Human CHFR; E3 ubiquitin-protein ligase CHFR; Checkpoint with forkhead and RING finger domains protein; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR	Human	E. coli
	The CHFR protein is an E3 ubiquitin protein ligase that delays mitosis by microtubule toxicants. CHFR Protein, Human is the recombinant human-derived CHFR protein, expressed by E. coli , with tag free. The total length of CHFR Protein, Human is 663 a.a., .

HY-P701541

	CHFR Protein, Human (His) CHFR; E3 ubiquitin-protein ligase CHFR; Checkpoint with forkhead and RING finger domains protein; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR	Human	E. coli
	The CHFR protein is an E3 ubiquitin protein ligase that delays mitosis by microtubule toxicants. CHFR Protein, Human (His) is the recombinant human-derived CHFR protein, expressed by E. coli , with N-6*His labeled tag. The total length of CHFR Protein, Human (His) is 663 a.a., .

HY-P70855

	MARCO Protein, Mouse (HEK293, His) Macrophage receptor MARCO; Marco; Macrophage receptor with collage	Mouse	HEK293
	MARCO Protein, a pattern recognition receptor (PRR), binds Gram-positive and Gram-negative bacteria, exhibiting a crucial role in unopsonized particle binding by alveolar macrophages. Furthermore, it interacts with the secretoglobin SCGB3A2. MARCO Protein forms disulfide-linked homotrimer structures that assemble into larger oligomers, providing an extensive surface area for interactions with substantial ligands. MARCO Protein, Mouse (HEK293, His) is the recombinant mouse-derived MARCO protein, expressed by HEK293 , with N-8*His labeled tag. The total length of MARCO Protein, Mouse (HEK293, His) is 449 a.a., with molecular weight of 55-65 kDa.

HY-P71583

	LAMTOR1 Protein, Human (His) C11orf59; LAMTOR1; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1; Lipid raft adaptor protein p18; LTOR1_HUMAN; p18; p27Kip1-releasing factor from RhoA; p27RF-Rho; PDRO; PP7157; Protein associated with DRMs and endosomes; Ragulator complex protein LAMTOR1; ragulator complex protein PDRO; Ragulator1; RhoA activator C11orf59	Human	E. coli
	The LAMTOR1 protein is an important component of the Ragulator complex and plays dual roles in amino acid sensing and mTORC1 activation. It acts as a guanine nucleotide exchange factor (GEF) for Rag GTPases and mediates their recruitment to the lysosomal membrane. LAMTOR1 Protein, Human (His) is the recombinant human-derived LAMTOR1 protein, expressed by E. coli , with N-His labeled tag. The total length of LAMTOR1 Protein, Human (His) is 160 a.a., with molecular weight of ~24 kDa.

HY-P70052

	CXADR Protein, Mouse (HEK293, Fc) 1 Publications Verification rMuCoxsackievirus and adenovirus receptor homolog/CXADR, Fc; Coxsackievirus and adenovirus receptor homolog; CAR; Cxadr; CVB3 BP	Mouse	HEK293
	CXADR protein is a key component of the epithelial apical junction complex, which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML. This interaction activates γ-δ T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase. CXADR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CXADR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CXADR Protein, Mouse (HEK293, Fc) is 218 a.a., with molecular weight of 50-70 kDa.

HY-P71641

	IFIH1 Protein, Human (His) CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140kDa; DEAD/H (Asp Glu Ala Asp/His) box polypeptide; DEAD/H box polypeptide; Helicard; Helicase with 2 CARD domains; Hlcd; MDA-5	Human	E. coli
	The IFIH1 protein is an innate immune receptor that detects viral nucleic acids and triggers an antiviral response. IFIH1 is critical for type I interferon induction and recognizes ligands such as mRNA lacking 2'-O-methylation and long double-stranded RNA. IFIH1 Protein, Human (His) is the recombinant human-derived IFIH1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IFIH1 Protein, Human (His) is 326 a.a., with molecular weight of ~41.5 kDa.

HY-P76746

	BCCIP Protein, Human (sf9) BRCA2 and CDKN1A-interacting protein; P21- and CDK-associated protein 1; TOK1	Human	Sf9 insect cells
	BCCIP proteins contribute to interphase microtubule organization and anchoring as well as spindle pole organization and stability during mitosis. BCCIP protein may induce cell cycle arrest by enhancing CDK2 inhibition and participate in DNA damage repair through homologous recombination with BRCA2. BCCIP Protein, Human (sf9) is the recombinant human-derived BCCIP protein, expressed by Sf9 insect cells , with tag free. The total length of BCCIP Protein, Human (sf9) is 314 a.a., with molecular weight of ~47 kDa.

HY-P70095

	DCBLD2 Protein, Human (HEK293, His) rHuDiscoidin, CUB and LCCL domain-containing protein 2/ DCBLD2, His; Discoidin; CUB and LCCL domain-containing protein 2; DCBLD2; CUB; LCCL and coagulation factor V/VIII-homology domains protein 1; Endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; CLCP1; ESDN;	Human	HEK293
	DCBLD2 Protein is a novel platelet membrane receptor that recruits TRAF6 through EGFR phosphorylation and stimulates AKT to promote tumorigenesis. The DCBLD2 Protein has multiple functions during development as well as in vascular and tumor biology, such as influencing cell proliferation and tumorigenesis. DCBLD2 Protein, Human (HEK293, His) is the recombinant human-derived DCBLD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DCBLD2 Protein, Human (HEK293, His) is 462 a.a., with molecular weight of 80-110 kDa.

HY-P76747

	BCCIP Protein, Human (sf9, His-GST) BRCA2 and CDKN1A-interacting protein; P21- and CDK-associated protein 1; TOK1	Human	Sf9 insect cells
	BCCIP proteins contribute to interphase microtubule organization and anchoring as well as spindle pole organization and stability during mitosis. BCCIP protein may induce cell cycle arrest by enhancing CDK2 inhibition and participate in DNA damage repair through homologous recombination with BRCA2. BCCIP Protein, Human (sf9, His-GST) is the recombinant human-derived BCCIP protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of BCCIP Protein, Human (sf9, His-GST) is 314 a.a., with molecular weight of ~65 kDa.

HY-P76288

	CRELD2 Protein, Mouse (HEK293, Fc) Cysteine-Rich with EGF-Like Domain Protein 2; CRELD2	Mouse	HEK293
	CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRELD2 Protein, Mouse (HEK293, Fc) is 350 a.a., with molecular weight of ~62.8 KDa.

HY-P76289

	CRELD2 Protein, Mouse (HEK293, His) Cysteine-Rich with EGF-Like Domain Protein 2; CRELD2	Mouse	HEK293
	CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRELD2 protein, expressed by HEK293 , with C-His labeled tag. The total length of CRELD2 Protein, Mouse (HEK293, His) is 328 a.a., with molecular weight of ~51.3-55 KDa.

HY-P701575

	KBTBD2 Protein, Human (Sf9) KBTBD2; Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1	Human	Sf9 insect cells
	KBTBD2 in the BCR E3 ubiquitin ligase complex is a key regulator in the insulin signaling pathway and affects the insulin sensitivity of adipocytes. Its effects are manifested by regulating PIK3R1/p85alpha abundance by coordinating the ubiquitination process for PIK3R1 degradation. KBTBD2 Protein, Human (Sf9) is the recombinant human-derived KBTBD2 protein, expressed by Sf9 insect cells , with tag free. The total length of KBTBD2 Protein, Human (Sf9) is 622 a.a., .

HY-P77099

	NCKIPSD Protein, Human (His) NCK-interacting protein with SH3 domain; VIP54; WISH; AF3P21; SPIN90	Human	E. coli
	NCKIPSD Protein, vital for stress fiber formation induced by active DRF1, stimulates N-WASP-induced ARP2/3 complex activation, independent of CDC42. Implicated in sarcomere maintenance, myofibril assembly, actin polymerization, and angiogenesis. Associates with vimentin, desmin, NCK, GRB2, and interacts with Helicobacter pylori toxin vacA, FHOD1, FASLG, and TMIGD2, showcasing its diverse cellular interactions. NCKIPSD Protein, Human (His) is the recombinant human-derived NCKIPSD protein, expressed by E. coli, with N-His labeled tag. The total length of NCKIPSD Protein, Human (His) is 244 a.a., with molecular weight of ~33-45 kDa.

HY-P701458

	AMSH Protein, Human STAMBP; STAM-binding protein; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase	Human	E. coli
	AMSH is a zinc metalloprotease that selectively cleaves "Lys-63"-linked polyubiquitin chains, but not "Lys-48"-linked chains. It plays a critical regulatory role in signaling in IL-2 and GM-CSF mediated pathways, acting as a positive BMP signaling modulator against SMAD6 and SMAD7 inhibition. AMSH Protein, Human is the recombinant human-derived AMSH protein, expressed by E. coli , with tag free. The total length of AMSH Protein, Human is 423 a.a., .

HY-P71370

	TMIGD2 Protein, Human (HEK293, His) Transmembrane and immunoglobulin domain-containing protein 2; Immunoglobulin and proline-rich receptor 1; IGPR1; TMIGD2	Human	HEK293
	TMIGD2 is a multifaceted protein actively involved in cellular processes, including cell-cell interactions, migration, and angiogenesis. Its interaction with HHLA2 enhances T cell proliferation and cytokine production through AKT-dependent signaling during TCR-mediated activation. TMIGD2 Protein, Human (HEK293, His) is the recombinant human-derived TMIGD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TMIGD2 Protein, Human (HEK293, His) is 128 a.a., with molecular weight of ~30.0 kDa.

HY-P77249

	TMIGD2 Protein, Human (HEK293, Fc) Transmembrane and immunoglobulin domain-containing protein 2; Immunoglobulin and proline-rich receptor 1; IGPR1; TMIGD2	Human	HEK293
	TMIGD2, a multifaceted protein, actively participates in cellular processes, including cell-cell interaction, migration, and angiogenesis. Its interaction with HHLA2 enhances T-cell proliferation and cytokine production through AKT-dependent signaling during TCR-mediated activation. TMIGD2 may engage in homophilic interactions, regulating cell-cell communication. Interactions with CACNB2, DST, MIA, and NCKIPSD indicate its involvement in diverse cellular pathways, emphasizing its versatile functions in essential activities. TMIGD2 Protein, Human (HEK293, Fc) is the recombinant human-derived TMIGD2 protein, expressed by HEK293, with C-hFc labeled tag. The total length of TMIGD2 Protein, Human (HEK293, Fc) is 150 a.a., with molecular weight of ~40.9 KDa.

HY-P702199

	ADIPOR1 Protein, Human (Cell-Free) Adiponectin receptor protein 1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I	Human	E. coli Cell-free
	ADIPOR1 Protein, a receptor for adiponectin (ADIPOQ), crucially regulates glucose and lipid metabolism, maintaining homeostasis and healthy body weight. Upon ADIPOQ binding, ADIPOR1 activates AMPK, promoting fatty acid oxidation and glucose uptake while inhibiting gluconeogenesis. ADIPOR1 interacts with APPL2, negatively regulating signaling, and with APPL1, enhancing ADIPOQ-induced recruitment and positive regulation of adiponectin signaling. ADIPOR1 Protein, Human (Cell-Free) is the recombinant human-derived ADIPOR1 protein, expressed by E. coli Cell-free , with tag free. The total length of ADIPOR1 Protein, Human (Cell-Free) is 287 a.a., with molecular weight of 33.0 kDa.

HY-P70049

	CXADR Protein, Human (HEK293, His) rHuCoxsackievirus and adenovirus receptor/CXADR, His ; Coxsackievirus and Adenovirus Receptor; CAR; hCAR; CVB3-Binding Protein; Coxsackievirus B-Adenovirus Receptor; HCVADR; CXADR; CAR	Human	HEK293
	CXADR proteins are components of the epithelial apical junction complex and, as cell adhesion molecules, are critical for the integrity of tight junctions. CXADR Protein, Human (HEK293, His) is the recombinant human-derived CXADR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CXADR Protein, Human (HEK293, His) is 218 a.a., with molecular weight of ~32.0 kDa.

HY-P701576

	KBTBD2 Protein, Human (Sf9, His, Strep) KBTBD2; Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1	Human	Sf9 insect cells
	KBTBD2 in the BCR E3 ubiquitin ligase complex is a key regulator in the insulin signaling pathway and affects the insulin sensitivity of adipocytes. Its effects are manifested by regulating PIK3R1/p85alpha abundance by coordinating the ubiquitination process for PIK3R1 degradation. KBTBD2 Protein, Human (Sf9, His, Strep) is the recombinant human-derived KBTBD2 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of KBTBD2 Protein, Human (Sf9, His, Strep) is 622 a.a., .

HY-P70107

	CGREF1 Protein, Human (282a.a, HEK293, His) rHuCell growth regulator with EF hand domain protein 1/CGREF1, His; Cell Growth Regulator with EF Hand Domain Protein 1; Cell Growth Regulatory Gene 11 Protein; Hydrophobestin; CGREF1; CGR11	Human	HEK293

HY-P701459

	AMSHLP Protein, Human (His) STAMBP; STAM-binding protein; Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase	Human	E. coli
	AMSHLP is a zinc metalloprotease that selectively cleaves "Lys-63" linked polyubiquitin chains and acts as a positive regulator of the TORC1 signaling pathway. It specifically deubiquitinates SESN2, disrupts its interaction with the GATOR2 complex and inhibits SESN2-mediated regulation of TORC1. AMSHLP Protein, Human (His) is the recombinant human-derived AMSHLP protein, expressed by E. coli , with N-6*His labeled tag. The total length of AMSHLP Protein, Human (His) is 435 a.a., .

HY-P701614

	WDHD1 Protein, Human (HEK293, FLAG) WDHD1; WD repeat and HMG-box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; and-1	Human	HEK293
	WDHD1 Protein is a core replisome component that serves as a replication initiation factor. It directly binds to the CMG complex, acting as a hub to recruit other proteins to the replication fork. WDHD1 interacts with POLA1, MCM10, DNA2, CDC45, and GINS2, linking it to the CMG helicase complex. WDHD1 Protein, Human (HEK293, FLAG) is the recombinant human-derived WDHD1 protein, expressed by HEK293 , with C-Flag labeled tag. The total length of WDHD1 Protein, Human (HEK293, FLAG) is 1128 a.a., .

HY-P702200

	ADIPOR1 Protein, Human (Cell-Free, His, Flag) Adiponectin receptor protein 1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I	Human	E. coli Cell-free
	ADIPOR1 Protein, a receptor for adiponectin (ADIPOQ), crucially regulates glucose and lipid metabolism, maintaining homeostasis and healthy body weight. Upon ADIPOQ binding, ADIPOR1 activates AMPK, promoting fatty acid oxidation and glucose uptake while inhibiting gluconeogenesis. ADIPOR1 interacts with APPL2, negatively regulating signaling, and with APPL1, enhancing ADIPOQ-induced recruitment and positive regulation of adiponectin signaling. ADIPOR1 Protein, Human (Cell-Free, His, Flag) is the recombinant human-derived ADIPOR1 protein, expressed by E. coli Cell-free , with N-6*His, N-Flag labeled tag. The total length of ADIPOR1 Protein, Human (Cell-Free, His, Flag) is 287 a.a., with molecular weight of 34.8 kDa.

HY-P74351

	CART Protein, Human (HEK293) Cocaine- and amphetamine-regulated transcript protein; CART; CARTPT	Human	HEK293
	CART Protein, a satiety factor, intricately regulates feeding in connection with leptin and neuropeptide Y. It effectively suppresses regular and starvation-triggered feeding, robustly inhibiting neuropeptide Y-initiated feeding within the hypothalamus. Additionally, CART protein plays a pivotal role in fostering neuronal development and survival in vitro, extending beyond its appetite regulation function. CART Protein, Human (HEK293) is the recombinant human-derived CART protein, expressed by HEK293 , with tag free. The total length of CART Protein, Human (HEK293) is 89 a.a., with molecular weight of ~11 kDa.

HY-P701646

	TNIK Protein, Human (Sf9) TNIK; TRAF2 and NCK-interacting protein kinase	Human	Sf9 insect cells
	TNIK protein is a key activator of the Wnt signaling pathway and regulates gene expression by phosphorylating TCF4/TCF7L2 at the promoter of Wnt target genes. TNIK is located upstream of the JUN N-terminal pathway and contributes to the complex Wnt signaling cascade. TNIK Protein, Human (Sf9) is the recombinant human-derived TNIK protein, expressed by Sf9 insect cells , with tag free. The total length of TNIK Protein, Human (Sf9) is 304 a.a., .

HY-P76700

	VTI1A Protein, Human (HEK293, His) Vesicle transport through interaction with t-SNAREs homolog 1A; Vti1-rp2	Human	HEK293
	VTI1A Protein, a V-SNARE, mediates vesicle transport by interacting with t-SNAREs on target membranes, facilitating lipid bilayer fusion. It plays a role in vesicular transport from late endosomes to the trans-Golgi network. Collaborating with VAMP7, it participates in a non-conventional RAB1-dependent route to the cell surface used by KCNIP1 and KCND2. VTI1A interacts with SNARE complexes containing STX5 or STX6, NAPA, and to a lesser extent, NAPG. It is part of a complex with STX6, STX12, VAMP4, and VTI1A. VTI1A Protein, Human (HEK293, His) is the recombinant human-derived VTI1A protein, expressed by HEK293 , with N-His labeled tag. The total length of VTI1A Protein, Human (HEK293, His) is 187 a.a., with molecular weight of ~29 & 25 & 20 kDa, respectively.

HY-P76701

	VTI1A Protein, Human (HEK293, Fc) Vesicle transport through interaction with t-SNAREs homolog 1A; Vti1-rp2	Human	HEK293
	VTI1A Protein, a V-SNARE, mediates vesicle transport by interacting with t-SNAREs on target membranes, facilitating lipid bilayer fusion. It plays a role in vesicular transport from late endosomes to the trans-Golgi network. Collaborating with VAMP7, it participates in a non-conventional RAB1-dependent route to the cell surface used by KCNIP1 and KCND2. VTI1A interacts with SNARE complexes containing STX5 or STX6, NAPA, and to a lesser extent, NAPG. It is part of a complex with STX6, STX12, VAMP4, and VTI1A. VTI1A Protein, Human (HEK293, Fc) is the recombinant human-derived VTI1A protein, expressed by HEK293 , with N-mFc labeled tag. The total length of VTI1A Protein, Human (HEK293, Fc) is 187 a.a., with molecular weight of ~48.5 kDa.

HY-P701615

	WDHD1 Protein, Human (HEK293, His, Strep) WDHD1; WD repeat and HMG-box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; and-1	Human	HEK293
	WDHD1 Protein is a core replisome component that serves as a replication initiation factor. It directly binds to the CMG complex, acting as a hub to recruit other proteins to the replication fork. WDHD1 interacts with POLA1, MCM10, DNA2, CDC45, and GINS2, linking it to the CMG helicase complex. WDHD1 Protein, Human (HEK293, His, Strep) is the recombinant human-derived WDHD1 protein, expressed by HEK293 , with N-10*His, N-Strep labeled tag. The total length of WDHD1 Protein, Human (HEK293, His, Strep) is 1128 a.a., .

HY-P702201

	ADIPOR1 Protein, Human (Cell-Free, His, SUMO, Myc) Adiponectin receptor protein 1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I	Human	E. coli Cell-free
	ADIPOR1 Protein, a receptor for adiponectin (ADIPOQ), crucially regulates glucose and lipid metabolism, maintaining homeostasis and healthy body weight. Upon ADIPOQ binding, ADIPOR1 activates AMPK, promoting fatty acid oxidation and glucose uptake while inhibiting gluconeogenesis. ADIPOR1 interacts with APPL2, negatively regulating signaling, and with APPL1, enhancing ADIPOQ-induced recruitment and positive regulation of adiponectin signaling. ADIPOR1 Protein, Human (Cell-Free, His, SUMO, Myc) is the recombinant human-derived ADIPOR1 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc, N-SUMO labeled tag. The total length of ADIPOR1 Protein, Human (Cell-Free, His, SUMO, Myc) is 375 a.a., with molecular weight of 62.6 kDa.

HY-P70109

	CDCP1 Protein, Human (313a.a, HEK293, His) rHuCUB domain-containing protein 1/CDCP1, His; CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD318; TRASK	Human	HEK293
	CDCP1 protein may be involved in cell adhesion and extracellular matrix association. Phosphorylation of CDCP1 may regulate the balance between anchorage and migration, proliferation, and differentiation. CDCP1 Protein, Human (313a.a, HEK293, His) is the recombinant human-derived CDCP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CDCP1 Protein, Human (313a.a, HEK293, His) is 313 a.a., with molecular weight of ~55.0 kDa.

HY-P701098

	STAT3 Protein, Human (Full Length, His) STAT3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer and activator of transcription 3; APRF	Human	E. coli
	STAT3 is a signal transducer and transcriptional activator that coordinates diverse cellular processes in response to growth factors and cytokines such as interleukin-6 and KITLG/SCF. Upon activation, STAT3 recruits coactivators to target gene promoters, thereby affecting proliferation, differentiation, and immune responses. STAT3 Protein, Human (Full Length, His) is the recombinant human-derived STAT3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of STAT3 Protein, Human (Full Length, His) is 770 a.a., with molecular weight of ~92.1 kDa.

HY-P74350

	CART Protein, Human (HEK293, Fc) Cocaine- and amphetamine-regulated transcript protein; CART; CARTPT	Human	HEK293
	CART Protein, a satiety factor, intricately regulates feeding in connection with leptin and neuropeptide Y. It effectively suppresses regular and starvation-triggered feeding, robustly inhibiting neuropeptide Y-initiated feeding within the hypothalamus. Additionally, CART protein plays a pivotal role in fostering neuronal development and survival in vitro, extending beyond its appetite regulation function. CART Protein, Human (HEK293, Fc) is the recombinant human-derived CART protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CART Protein, Human (HEK293, Fc) is 89 a.a., with molecular weight of ~37 kDa.

HY-P701645

	TNIK Protein, Human (Sf9, His) TNIK; TRAF2 and NCK-interacting protein kinase	Human	Sf9 insect cells
	TNIK protein is a key activator of the Wnt signaling pathway and regulates gene expression by phosphorylating TCF4/TCF7L2 at the promoter of Wnt target genes. TNIK is located upstream of the JUN N-terminal pathway and contributes to the complex Wnt signaling cascade. TNIK Protein, Human (Sf9, His) is the recombinant human-derived TNIK protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of TNIK Protein, Human (Sf9, His) is 304 a.a., .

HY-P76285

	CRELD1 Protein, Human (HEK293, His) Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1; CIRRIN	Human	HEK293
	CRELD1 Protein, acting as a protein disulfide isomerase, aids in the correct folding and assembly of proteins, crucial for cellular homeostasis. It also contributes to the proper localization of acetylcholine receptors (AChRs) to the plasma membrane, emphasizing its significance in maintaining protein structure and membrane receptor distribution. CRELD1 Protein, Human (HEK293, His) is the recombinant human-derived CRELD1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CRELD1 Protein, Human (HEK293, His) is 362 a.a., with molecular weight of 40-50 KDa.

HY-P76286

	CRELD1 Protein, Mouse (HEK293, Fc) Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1; CIRRIN	Mouse	HEK293
	The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRELD1 Protein, Mouse (HEK293, Fc) is 362 a.a., with molecular weight of ~63 KDa.

Cat. No.	Product Name	Chemical Structure

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-W004282S

Undecanoic acid-d21
Undecanoic acid-d₂₁ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].

HY-W004282S1

Undecanoic acid-d3
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-W004282S2

Undecanoic acid-d2
Undecanoic acid-d₂ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-Y0921S3

(±)-1,2-Propanediol-13C3
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-N0733S2

Glucosamine-13C,15N hydrochloride
Glucosamine- ¹³C, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i

HY-B0271S1

Pyrazinamide-13C,15N
Pyrazinamide- ¹³C, ¹⁵N is ¹⁵N and ¹³C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.

HY-N0650S6

L-Serine1-13C,15N
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0367S

Trans-Anethole-d3
Trans-Anethole-d₃ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria . α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption .

HY-A0061S

Trifluridine-13C,15N2
Trifluridine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].

HY-Y0418S

Dulcite-13C

Dulcite- ¹³C is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-13458S1

Droxidopa-13C2,15N hydrochloride
Droxidopa- ¹³C₂, ¹⁵N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].

HY-66005S4

Acetaminophen-13C2,15N
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].

HY-15236S1

PSI-6206-d1,13C,15N2
PSI-6206-d1, ¹³C, ¹⁵N₂ is ¹⁵N and ¹³C labeled PSI-6206 (HY-15236). PSI-6206 (RO 2433) is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC₉₀ of >100 μM.

HY-13613S2

Dutasteride-13C,15N,d
Dutasteride- ¹³C, ¹⁵N,d is ¹⁵N and deuterated labeled Dutasteride (HY-13613). Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT .

HY-B0389S10

D-Glucose-13C
D-Glucose- ¹³C is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S29

D-Glucose-18O
D-Glucose- ¹⁸O is the ¹⁸O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules

HY-N5142S

α-Terpineol-d3
α-Terpineol-d₃ is the deuterium labeled α-Terpineol[1]. α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria[2].α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption[2].

HY-Y1250S6

Fmoc-Gly-OH-13C2,15N
Fmoc-Gly-OH- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

HY-N1480S

(-)-Fucose-13C
(-)-Fucose- ¹³C is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]

HY-125818S2

Cytidine-5'-triphosphate-13C,d1 dilithium

Cytidine-5'-triphosphate- ¹³C,d₁ (Cytidine triphosphate- ¹³C,d₁ dilithium; 5'-CTP- ¹³C,d₁) dilithium is deuterium and ¹³C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-W067028S

Semicarbazide-13C,15N2 hydrochloride

Semicarbazide- ¹³C, ¹⁵N₂ hydrochloride is ¹⁵N and ¹³C labeled Semicarbazide.
HY-Z0283S

Benzamide-15N

Benzamide- ¹⁵N is a ¹⁵N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].

HY-A0070AS1

Liothyronine-13C9,15N
Liothyronine- ¹³C₉, ¹⁵N is the ¹³C and ¹⁵N labeled Liothyronine[1]. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[2][3][4].

Cat. No.	Product Name	Application	Reactivity

HY-P81193

ADAMTS5 Antibody A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 5; A Disintigrin and Metalloproteinase with ThromboSpondin motif-5; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADAM TS 11; ADAM TS 5; ADAM TS5; ADAMTS 11; ADAMTS 5; ADAMTS11; ADMP 2; ADMP2; Aggrecanase 2; aggrecanase-2; FLJ36738; Implantin; ThromboSpondin motif-5.	WB; ELISA; IHC-P	Human, Mouse, Rat(predicted: Dog, Pig, Cow, Horse, Rabbit)
ADAMTS5 Antibody is an unconjugated, approximately 102 kDa, rabbit-derived, anti-ADAMTS5 polyclonal antibody. ADAMTS5 Antibody can be used for: WB, ELISA, IHC-P expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, rabbit background without labeling.

HY-P82565

SorLA Antibody (YA2310) SORL1; C11orf32; Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repe	WB, IHC-P	Human, Mouse, Rat

HY-P81434

BANK1 Antibody (YA1179)

BANK1; B-cell scaffold protein with ankyrin repeats
IHC-P Human
HY-P81619

BTLA Antibody (YA1364)

BTLA; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD antigen CD272
FC, ELISA Human

HY-P81998

Pirh2 Antibody (YA1743) RCHY1; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; RING finger and CHY zinc finger domain-containing protein 1; androgen receptor N-terminal-interacting protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; RING finger	WB	Human

HY-P83063

TRAF4 Antibody (YA2808) TRAF4; CART1; MLN62; RNF83; TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83	WB, ICC/IF, FC	Human, Mouse

HY-P80758

MSR1 Antibody Macrophage scavenger receptor types I and II; Macrophage acetylated LDL receptor I and II; Scavenger receptor class A member 1; CD204; MSR1; SCARA1	WB	Human, Mouse, Rat
MSR1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 50 kDa, targeting to MSR1. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80903

STAT4 Antibody STAT4; Signal transducer and activator of transcription 4	WB, IHC-P, IP	Human
STAT4 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 86 kDa, targeting to STAT4. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human.

HY-P82776

CLPTM1 Antibody (YA2521)

Cleft lip and palate transmembrane protein 1
WB, IP Human
HY-P81473

IGJ Antibody (YA1218)

IGJ; Immunoglobulin J Chain; IGJ; Joining chain of multimeric IgA and IgM
IHC-P Human
HY-P83054

FAM50A Antibody (YA2799)

family with sequence similarity 50 member A; 9F; XAP5; HXC26; HXC-26; DXS9928E
WB, IHC-F, IHC-P, ICC/IF, IP Human, Mouse, Rat, Hamster

HY-P80680

FTO Antibody FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein	WB, IHC-P	Human
FTO Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 58 kDa, targeting to FTO. It can be used for WB,IHC-P assays with tag free, in the background of Human.

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<i>Trichophyton rubrum</i> and <i>Trichophyton mentagrophytes</i> with MICs of 62.5 μg/mL<sup>[1]</sup>.

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Fluorescent Dye

Biochemical Assay Reagents

Peptides

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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

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